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VitalSource e-Book for Successful Randomized Trials VitalSource e-Book for Successful Randomized Trials
VitalSource e-Book for Successful Randomized Trials

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VitalSource e-Book for Successful Randomized Trials

9781451103564
Michael Domanski MD, Sonja McKinlay PhD
ISBN/ISSN:
9781451103564
Publication Date:
December 17, 2010
2010-12-17
9781451103564
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This handbook is a ready reference on the theory and operation of modern large, multicenter randomized clinical trials, which have ...
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  • This handbook is a ready reference on the theory and operation of modern large, multicenter randomized clinical trials, which have come to be the basis of evidence-based medicine. Written in a concise, engaging style geared to physicians, the book explains the rationale and theoretical foundations for clinical trials, the components of modern clinical trials including their functions and interactions, and practical considerations in the design and implementation of these studies including an introduction to the economics and business aspects.
  • ISBN/ISSN
    9781451103564
    Product Format
    Vitalsource Interactive eBook
    Publication Date
    December 17, 2010
  • Michael Domanski MD
    National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD
    Sonja McKinlay PhD
    President, New England Research Institutes, Inc., Watertown, MA
  • Contributors
    Preface
    Foreword
    Abbreviations

    SECTION I Clinical Trial Principles
    1. Randomized Clinical Trials
    MICHAEL J. DOMANSKI AND SONJA MCKINLAY
    2. Designing Clinical Trials
    SUSAN F. ASSMANN
    3. Randomization: What It Is and How to Do It
    CATHERINE E. HEWITT AND DAVID J. TORGERSON
    4. Setting Sample Size for Randomized Clinical Trials
    XIN TIAN, SONJA M. MCKINLAY, AND NANCY L. GELLER
    5. Analytic Approach and Methods
    LYNN A. SLEEPER
    6. Ethical Considerations
    LAWRENCE M. FRIEDMAN AND ELEANOR B. SCHRON

    SECTION II Large Multicenter Trials: Structure and Conduct
    7. Study Organization and Governance
    FLEUR HUDSON, JULIE BAKOBAKI, AND ABDEL BABIKER
    8. Quality Control and Quality Assurance
    FLORA S. SIAMI
    9. Quality Assurance: Prevention of Missing Data
    JAMES NEATON

    SECTION III The Future
    10. Surrogate Endpoints
    ROBERT FIORENTINO
    11. Registries
    HESHA DUGGIRALA
    12. Gazing into the Crystal Ball: The Future of Randomized Clinical Trials
    MICHAEL J. DOMANSKI, SONJA M. MCKINLAY, AND MARC PFEFFER

    Index
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VitalSource e-Book for Successful Randomized Trials

VitalSource e-Book for Successful Randomized Trials

ISBN/ISSN: 9781451103564
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